Ownership Profile

Shareholder Breakdown
Shareholder Holders Values ($) % O/S Shares
Institution 56 170 97.58 16,885,868
Mutual Fund 37 46 14.10 2,439,795
Institutional Shareholder Rotation
Shareholder Holders Values Change ($) % O/S Shares Change
Buyers 22 9.96 4.67 808,266
Sellers 18 -2.95 1.40 -241,861
Net -- 7.01 3.27 566,405
Institutional Shareholder Concentration
Shareholder Values ($) % O/S Shares
Top 10 Inst. 133 78.85 13,644,713
Top 20 Inst. 165.44 95.31 16,493,567
Top 50 Inst. 169.96 97.57 16,884,331
Total Inst. 169.96 97.57 16,884,331
Institutional Shareholder Style
Shareholder Holders Values ($) % O/S Shares
Index 7 11 5.17 895,145
CoreGrowth 9 5 2.55 440,828
Growth 2 25 12.01 2,078,580
IncomeValue 1 0 0.07 12,148
BrokerDealer 3 1 0.28 48,330
GARP 3 1 0.25 42,411
HedgeFund 13 79 37.82 6,544,741
SectorSpecific 1 17 8.07 1,397,100
VCPrivateEquity 1 3 1.56 270,289
CoreValue 2 0 0.04 6,633
DeepValue 3 0 0.04 6,919
Top Holders: Institutional Investor
Holder Shares Held % O/S Shares Change Filing Date
EcoR1 Capital, LLC 2,943,164 17.01 0 12/31/2016
Jennison Associates LLC 2,077,830 12.01 47,785 12/31/2016
OrbiMed Advisors, LLC 1,397,100 8.07 0 12/31/2016
Zlotnick Adam 1,321,009 7.63 0 03/31/2016
Acuta Capital Partners, LLC 976,599 5.64 662,388 12/31/2016
QVT Financial LP 791,586 4.57 -16,015 12/31/2016
Perceptive Advisors LLC 714,354 4.13 -63,315 12/31/2016
Small Derek A 634,391 3.67 10,000 03/31/2016
Lopatin Uri A 626,651 3.62 5,000 03/31/2016
The Vanguard Group, Inc. 453,236 2.62 18,862 12/31/2016
Rock Springs Capital Management LP 390,000 2.25 0 12/31/2016
Putnam Investment Management, L.L.C. 364,550 2.11 -5,450 12/31/2016
Millennium Management LLC 359,905 2.08 -3,799 12/31/2016
DiMarchi (Richard D) 319,240 1.84 8,415 03/31/2016
BlackRock Institutional Trust Company, N.A. 313,872 1.81 852 12/31/2016
venBio Select Advisor LLC 270,289 1.56 2,170 12/31/2016
Baker Bros. Advisors LP 250,000 1.44 0 12/31/2016
Geode Capital Management, L.L.C. 74,038 0.43 1,684 12/31/2016
K2 Advisors L.L.C. 53,724 0.31 2,662 12/31/2016
Dimensional Fund Advisors, L.P. 46,027 0.27 4,568 12/31/2016
Northern Trust Investments, Inc. 41,811 0.24 9,702 12/31/2016
William Blair & Company, L.L.C. 40,850 0.24 0 12/31/2016
Jacobs Levy Equity Management, Inc. 40,768 0.24 0 12/31/2016
Susquehanna Financial Group, LLLP 31,419 0.18 16,697 12/31/2016
Ellison (Russell H) 21,600 0.12 0 03/31/2016
Ringo (WilliamRJr) 20,465 0.12 0 03/31/2016
Barrett (David Jonathan) 19,936 0.12 0 03/31/2016
Simplex Trading, LLC 16,910 0.10 12,025 03/31/2017
National Asset Management, Inc. 14,000 0.08 -5,757 12/31/2016
BNY Mellon Asset Management 12,148 0.07 -772 12/31/2016
California Public Employees' Retirement System 11,240 0.06 0 12/31/2016
Deutsche Asset Management Americas 9,400 0.05 9,400 12/31/2016
Vericimetry Advisors LLC 9,023 0.05 1,000 10/31/2016
Northern Trust Global Investments 8,342 0.05 0 12/31/2016
Altig (Anthony E) 8,000 0.05 0 03/31/2016
Morgan Stanley Wealth Management 6,380 0.04 -1,675 12/31/2016
Acadian Asset Management LLC 4,242 0.02 4,242 12/31/2016
Guggenheim Investments 4,216 0.02 -901 02/28/2017
TFS Capital LLC 3,841 0.02 3,841 07/31/2016
First New York Capital Corp. 3,800 0.02 3,800 12/31/2016
Segantii Capital Management Limited 3,000 0.02 3,000 12/31/2016
BlackRock Financial Management, Inc. 2,704 0.02 0 12/31/2016
BlackRock Investment Management, LLC 2,417 0.01 -131 12/31/2016
AXA Rosenberg Investment Management LLC 2,417 0.01 0 01/31/2017
Group One Trading, L.P. 1,700 0.01 999 12/31/2016
Dimensional Fund Advisors, Ltd. 1,653 0.01 0 11/30/2016
JP Morgan Asset Management 937 0.01 937 08/31/2015
Invesco PowerShares Capital Management LLC 768 0.00 768 05/31/2016
Thompson, Davis & Co., Inc. (Asset Management) 750 0.00 -14,036 12/31/2016

Ownership data is provided by Thompson Reuters, a third party service, and Assembly Biosciences, Inc. does not maintain or provide information directly to this service.

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