Assembly Biosciences Announces Multiple Abstracts Highlighting HBV Core Inhibitor Portfolio Accepted for Oral and Poster Presentations at EASL 2019
Assembly had four abstracts accepted highlighting its HBV core protein inhibitor pipeline, including late breaker presentations on the interim results from the Phase 2a studies of ABI-H0731 and final results of the recently completed ABI-H2158 Phase 1a study. In addition, Assembly has an oral presentation on the preclinical profile of its third core inhibitor and a poster on the turnover rate of cccDNA. The late breaker abstract for ABI-H0731 has been selected for press release coverage at ILC 2019 and will only be made available at the time of presentation. The abstract was also selected for inclusion in the ‘Best of ILC’ presentation.
“We are proud to have several abstracts accepted at EASL 2019 for each of our three core inhibitors and one highlighting our continuing research efforts on the turnover rate of cccDNA,” said
Title: Interim safety and efficacy results of the ABI-H0731 phase 2a program exploring the combination of ABI-H0731 with Nuc therapy in treatment-naive and treatment-suppressed chronic hepatitis B patients
Session: Late breaker
Location: Main Plenary
Title: Preclinical profile of HBV core protein inhibitor, ABI-H3733, a potent inhibitor of cccDNA generation in HBV infected cells
Session: Parallel session: Hepatitis B – drug development
Location: Hall C2
Title: Phase 1a Study of the Safety, Tolerability and Pharmacokinetics of ABI-H2158, a Novel Second-Generation HBV Core Inhibitor, in
Session: Late breaker poster
Title: Rapid turnover of HBV cccDNA in nucleoside-treated chronic hepatitis B patients during drug resistance emergence and breakthrough
Session: Poster tour: Viral hepatitis B/D: Clinical aspects except therapy
Presenter: Qi Huang, PhD, Vice President, Virology Discovery and Chief Scientific Officer –
The abstracts that are now available can be accessed from the online congress program: https://ilc-congress.eu/
About Assembly Biosciences
The information in this press release contains forward-looking statements regarding future events, including statements about the clinical and therapeutic potential of core inhibitors, including ABI-H0731, ABI-H2158 and ABI-H3733. Certain forward-looking statements may be identified by reference to a future period or by use of forward-looking terminology such as “may” and “potential.” Assembly intends such forward-looking statements to be covered by the safe harbor provisions contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. More information about the risks and uncertainties faced by Assembly are more fully detailed under the heading “Risk Factors” in Assembly's Annual Report on Form 10-K for the year ended December 31, 2018 filed with the Securities and Exchange Commission. Except as required by law, Assembly assumes no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise.
Source: Assembly Biosciences, Inc.