1001 - Document - Document And Entity Information link:presentationLink link:definitionLink link:calculationLink 1002 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:definitionLink link:calculationLink 1003 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:definitionLink link:calculationLink 1004 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:presentationLink link:definitionLink link:calculationLink 1005 - Statement - CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY link:presentationLink link:definitionLink link:calculationLink 1006 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:definitionLink link:calculationLink 1007 - Disclosure - Nature of Business link:presentationLink link:definitionLink link:calculationLink 1008 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements link:presentationLink link:definitionLink link:calculationLink 1009 - Disclosure - Investments in Marketable Securities link:presentationLink link:definitionLink link:calculationLink 1010 - Disclosure - Property, Plant and Equipment, Net link:presentationLink link:definitionLink link:calculationLink 1011 - Disclosure - Accrued Expenses link:presentationLink link:definitionLink link:calculationLink 1012 - Disclosure - Stockholders' Equity link:presentationLink link:definitionLink link:calculationLink 1013 - Disclosure - Stock-Based Compensation link:presentationLink link:definitionLink link:calculationLink 1014 - Disclosure - Collaboration Agreement link:presentationLink link:definitionLink link:calculationLink 1015 - Disclosure - Milestones and Research Agreements link:presentationLink link:definitionLink link:calculationLink 1016 - Disclosure - Income Taxes link:presentationLink link:definitionLink link:calculationLink 1017 - Disclosure - Commitments and Contingencies link:presentationLink link:definitionLink link:calculationLink 1018 - Disclosure - Employee Benefit Plan link:presentationLink link:definitionLink link:calculationLink 1019 - Disclosure - Selected Quarterly Financial Data link:presentationLink link:definitionLink link:calculationLink 1020 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements (Policies) link:presentationLink link:definitionLink link:calculationLink 1021 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements (Tables) link:presentationLink link:definitionLink link:calculationLink 1022 - Disclosure - Investments in Marketable Securities (Tables) link:presentationLink link:definitionLink link:calculationLink 1023 - Disclosure - Property, Plant and Equipment, Net (Tables) link:presentationLink link:definitionLink link:calculationLink 1024 - Disclosure - Accrued Expenses (Tables) link:presentationLink link:definitionLink link:calculationLink 1025 - Disclosure - Stock-Based Compensation (Tables) link:presentationLink link:definitionLink link:calculationLink 1026 - Disclosure - Collaboration Agreement (Tables) link:presentationLink link:definitionLink link:calculationLink 1027 - Disclosure - Income Taxes (Tables) link:presentationLink link:definitionLink link:calculationLink 1028 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:definitionLink link:calculationLink 1029 - Disclosure - Selected Quarterly Financial Data (Tables) link:presentationLink link:definitionLink link:calculationLink 1030 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements (Details) link:presentationLink link:definitionLink link:calculationLink 1031 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements (Details 1) link:presentationLink link:definitionLink link:calculationLink 1032 - Disclosure - Summary of Significant Accounting Policies and Recent Accounting Pronouncements - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1033 - Disclosure - Investments in Marketable Securities (Details) link:presentationLink link:definitionLink link:calculationLink 1034 - Disclosure - Investments in Marketable Securities - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1035 - Disclosure - Property, Plant and Equipment, Net (Details) link:presentationLink link:definitionLink link:calculationLink 1036 - Disclosure - Property, Plant and Equipment, Net - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1037 - Disclosure - Accrued Expenses (Details) link:presentationLink link:definitionLink link:calculationLink 1038 - Disclosure - Stockholders' Equity - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1039 - Disclosure - Stock-Based Compensation (Details) link:presentationLink link:definitionLink link:calculationLink 1040 - Disclosure - Stock-Based Compensation (Details 1) link:presentationLink link:definitionLink link:calculationLink 1041 - Disclosure - Stock-Based Compensation (Details 2) link:presentationLink link:definitionLink link:calculationLink 1042 - Disclosure - Stock-Based Compensation (Details 3) link:presentationLink link:definitionLink link:calculationLink 1043 - Disclosure - Stock-Based Compensation - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1044 - Disclosure - Collaboration Agreement (Details) link:presentationLink link:definitionLink link:calculationLink 1045 - Disclosure - Collaboration Agreement (Details 1) link:presentationLink link:definitionLink link:calculationLink 1046 - Disclosure - Collaboration Agreement - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1047 - Disclosure - Milestones and Research Agreements - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1048 - Disclosure - Income Taxes (Details) link:presentationLink link:definitionLink link:calculationLink 1049 - Disclosure - Income Taxes (Details 1) link:presentationLink link:definitionLink link:calculationLink 1050 - Disclosure - Income Taxes (Details 2) link:presentationLink link:definitionLink link:calculationLink 1051 - Disclosure - Income Taxes - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1052 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:definitionLink link:calculationLink 1053 - Disclosure - Commitments and Contingencies - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1054 - Disclosure - Employee Benefit Plan - Additional Information (Details) link:presentationLink link:definitionLink link:calculationLink 1055 - Disclosure - Selected Quarterly Financial Data (Details) link:presentationLink link:definitionLink link:calculationLink