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Significant Accounting Policies [Table] Significant Accounting Policies [Table] Organization, Consolidation and Presentation of Financial Statements [Abstract] Local Phone Number Local Phone Number Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Preferred Stock, Shares Outstanding, Beginning Balance Preferred Stock, Shares Outstanding, Ending Balance Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share Subsidiary, Sale of Stock [Line Items] Subsidiary Sale Of Stock [Line Items] Operating Lease, Liability, Current Operating lease liabilities - short-term Warrants exercise price Warrant Excercise Price Warrant excercise price Retained Earnings [Member] Accumulated Deficit Payments to Acquire Property, Plant, and Equipment, Total Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Accrued Liabilities, Current [Abstract] Accrued expenses: Fair Value Measurements, Recurring and Nonrecurring [Table Text Block] Schedule of Fair Value of Financial Assets Document Transition Report Document Transition Report Expected equity financing completion date Expected Equity Financing Completion Date Expected equity financing completion date. Antidilutive Security, Excluded EPS Calculation [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Minimum [Member] Minimum Common Stock [Member] Common Stock Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Compensation expense: Issuance of common stock and warrants in a registered direct offering and a private placement, net of issuance costs Issuance of Common Stock and Warrants in Registered Direct Offering and Private Placement Net of Issuance Costs Value Issuance of common stock and warrants in registered direct offering and private placement net of issuance costs value. Accounts Payable and Accrued Liabilities Disclosure [Text Block] Other Accrued Expenses Represent non cash rent expense. Noncash Rent Expense Non-cash rent expense Common stock subject to purchase under employee stock purchase program. Common Stock Subject To Purchase Under Employee Stock Purchase Program [Member] Common stock subject to purchase under Employee Stock Purchase Plan Increase (Decrease) in Other Noncurrent Assets Other assets Additional Paid-in Capital [Member] Additional Paid-in Capital Stock outstanding during period shares reverse stock splits. Stock Outstanding During Period Shares Reverse Stock Splits Common stock shares outstanding due to reverse stock split Short-term marketable securities Fair Value, Short-term marketable securities Marketable securities Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Statement of Income Location, Balance [Domain] Income Statement Location Other Assets, Noncurrent Other assets Potential proceeds from equity financing Potential Proceeds from Equity Financing Potential proceeds from equity financing. Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Cash and cash equivalent gross unrealized gain. Cash And Cash Equivalent Gross Unrealized Gain Gross Unrealized Gain Potential proceeds from collaboration extension fees Potential Proceeds from Collaboration Extension Fees Potential proceeds from collaboration extension fees. Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Scenario [Domain] Collaborative and License Arrangement Disclosure. Collaborative And License Arrangement Disclosure [Text Block] Collaboration Agreements Common stock, $0.001 par value; 150,000,000 shares authorized as of June 30, 2024 and December 31, 2023; 6,345,561 and 5,482,752 shares issued and outstanding as of June 30, 2024 and December 31, 2023, respectively Common Stock, Value, Issued Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Cash and Cash Equivalents, Fair Value Disclosure Cash equivalents Fair Value Option, License and Collaboration Agreement Option, License and Collaboration Agreement [Member] Option, license and collaboration agreement. Gillead Collaboration Agreement Number of days volume considered for weighted average price to calculate premium Number of Days Volume Considered for Weighted Average Price to Calculate Premium Number of days volume considered for weighted average price to calculate premium. Measurement Frequency [Axis] Measurement Frequency Schedule of Accrued Liabilities [Table Text Block] Schedule of Other Accrued Expenses Commitments and Contingencies Commitments and contingencies The value of common stock authorized to issue in a public offering. Initial Public Offering Value Of Shares Authorized Initial public offering value of shares authorized Weighted Average Number of Shares Outstanding, Diluted Weighted average common shares outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted, Total Weighted average common shares outstanding - diluted Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Accounts receivable from collaboration Accounts Receivable, after Allowance for Credit Loss, Current Accounts Receivable, after Allowance for Credit Loss, Current, Total Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Research and Development Arrangement, Contract to Perform for Others, Type Available for sale debt securities accumulated gross unrealized loss before tax current. Available for Sale Debt Securities Accumulated Gross Unrealized Loss before Tax Current Gross Unrealized Loss, Short-term marketable securities Gilead Equity Agreements Equity Agreements [Member] Equity agreements. Weighted Average Number of Shares Outstanding, Diluted [Abstract] Denominator: Warrants expiration date Warrants and Rights Outstanding, Maturity Date Entity Small Business Entity Small Business Accrued interest receivable Accured Interest Receivable Accured Interest Receivable Stockholders' Equity Note, Stock Split, Conversion Ratio Reverse stock split ratio US Treasury Securities [Member] U.S. treasury securities Collaboration revenue recognized in the period from Collaboration Revenue Recognized In Period [Abstract] Collaboration revenue recognized in period [Abstract] Issuance of common stock for settlement of restricted stock units (RSUs) (in shares) Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures, Total Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities Deductions Contract With Customer Liability In Deduction Contract with customer liability in deduction. Restructuring and related cost incurred cost benefit Restructuring And Related Cost Incurred Cost Benefit Restructuring charges Restructuring costs incurred Measurement Frequency [Domain] Measurement Frequency Fair Value, Inputs, Level 3 [Member] Level 3 Percentage of premium to weighted average price immediately prior to date of purchase Percentage of Premium to Weighted Average Price Immediately Prior to Date of Purchase Percentage of premium to weighted average price immediately prior to date of purchase. Subsequent Event Subsequent Events [Text Block] Accounts Payable, Current Accounts payable Accounts Payable, Current, Total Lease expiration month and year Lease Expiration, Month And Year Lease expiration, month and year. Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]